AS-99 - Search Results | AbMole BioScience

About 5 results found for searched term "AS-99" (0.139 seconds)

Cat.No.	Name	Target
M7539	AS1517499	STAT
	AS1517499 is a novel and potent STAT6 inhibitor with an IC50 value of 21 nM.
M9729	diABZI STING agonist 1 (compound 3)	STING
	Tautomerism; CAS# 2138299-33-7
	diABZI STING agonist-1 (compound 3) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
M21504	AS-99 free base	Histone Methyltransferase
	AS-99 is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity.
M21505	AS-99	Histone Methyltransferase
	AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with antileukemic activity.
M21507	AS-99 TFA	Histone Methyltransferase
	AS-99 TFA is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity. In vivo, AS-99 TFA blocked cell proliferation, induced apoptosis and apoptosis, down-regulated MLL fusion target genes, and alleviated leukaemia.